Patient Guide to PRP Therapy for Knee Injuries and Degeneration


PRP (Platelet-Rich Plasma) therapy has emerged as a treatment option for knee injuries and degeneration, offering patients a non-surgical approach to alleviate pain, promote healing, and improve knee function. Here’s a patient guide to understanding prp knee conditions:

Understanding PRP Therapy

What is PRP?

– PRP is a concentration of platelets and growth factors derived from your own blood. These growth factors play a key role in tissue repair and regeneration.

Mechanism of Action:

– Healing: PRP promotes natural healing processes by enhancing tissue repair, stimulating collagen production, and reducing inflammation.

– Pain Relief: By reducing inflammation and promoting tissue regeneration, PRP aims to alleviate pain associated with knee injuries and degenerative conditions.

Conditions Treated

Common Knee Conditions:

– Osteoarthritis: PRP therapy may help manage pain and improve joint function by promoting cartilage repair and reducing inflammation in the knee joint.

– Tendon Injuries: Conditions like patellar tendonitis or chronic tendon injuries can benefit from PRP injections to stimulate tendon healing.

– Ligament Injuries: PRP may support healing and stability in cases of chronic ligament injuries affecting knee stability.

Procedure Overview

Before Treatment:

– A small amount of blood is drawn from your arm, similar to a routine blood test.


– The blood is processed in a centrifuge machine to separate and concentrate the platelets and growth factors into PRP.

Injection Process:

– The concentrated PRP is then injected into the affected area of the knee under sterile conditions, often guided by ultrasound for precision.

Benefits of PRP Therapy


– Non-Surgical: PRP therapy offers a non-surgical alternative to knee surgery, potentially reducing risks and downtime associated with invasive procedures.

– Natural Healing: Since PRP uses your own blood, it is considered a natural approach to promoting healing and tissue regeneration.

– Pain Relief: Many patients experience reduced pain and improved mobility following PRP injections, allowing for better quality of life.

What to Expect

Treatment Course:

– Depending on your condition and response, multiple PRP sessions may be recommended, typically spaced several weeks apart.

– Results may vary, and it may take several weeks to months to fully appreciate the benefits of PRP therapy.


– Recovery after PRP injections is usually minimal, with most patients able to resume normal activities shortly after treatment.

– Your healthcare provider may recommend activity modifications or physical therapy to optimize outcomes.


Patient Suitability:

– PRP therapy may not be suitable for everyone. Your healthcare provider will assess factors such as the severity of your knee condition, overall health, and previous treatments.

Combined Therapies:

– PRP therapy may be used in conjunction with other treatments like physical therapy, bracing, or medications to enhance outcomes and support long-term knee health.

Clinical Evidence

– Research: While clinical studies support the effectiveness of PRP therapy for knee conditions, results can vary among individuals. Continued research aims to refine treatment protocols and expand understanding of its benefits.


PRP therapy offers a promising avenue for individuals seeking non-surgical solutions to manage knee injuries and degeneration. By harnessing the body’s natural healing mechanisms, PRP aims to alleviate pain, promote tissue repair, and improve knee function. Consultation with a healthcare provider specializing in orthopedics or sports medicine is essential to determine if PRP therapy is appropriate for your specific condition and to develop a personalized treatment plan.